| Long name: |
ALEXA FLUOR 488 Conjugated, GGT1 Polyclonal Antibody |
| Also known as: |
Anti-GGT1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GGT1 |
| Specificity: |
This is a highly specific antibody against GGT1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
380-430/569 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GGT1 |
| Gene ID Number: |
2678 |
| Swiss Prot: |
P19440 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
In the presence of high concentrations of dipeptides and some amino acids, Initiates extracellular glutathione (GSH) breakdown, Isoform 3 seems to be inactive, It is part of the cell antioxidant defense mechanism, The metabolism of glutathione releases free glutamate and the dipeptide, and other gamma-glutamyl compounds, can also catalyze a transpeptidation reaction, cysteinyl-glycine, glutathione conjugates, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound, which is hydrolyzed to cysteine and glycine by dipeptidases, Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
D22S672 D22S732 CD224 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GGT1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
GGT1 |
| Short name: |
GGT1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, GGT1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4250 |
| Gene: |
GGT1 |
More about : GGT1 |
| Long gene name: |
gamma-glutamyltransferase 1 |
| Synonyms gene: |
GGT |
| Locus: |
22q11, 23 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M24903 |
| Entrez gene record: |
2678 |
| Pubmed identfication: |
8104871 18357469 |
| RefSeq identity: |
NM_013430 |
| Classification: |
Gamma-glutamyltransferases CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000030859 |