| Long name: |
FITC Conjugated, 5HTR2C Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
5HTR2C |
| Specificity: |
This is a highly specific antibody against 5HTR2C |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human 5HTR2C |
| Gene ID number: |
3358 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
5-HT), G-protein-coupled receptors, Jul 2008], RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims, This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, [provided by RefSeq, a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, thus modulating serotonergic neurotransmission in the central nervous system, where genomically encoded adenosine residues are converted to inosines, which activate phospholipase C and D signaling pathways, Serotonin (5-hydroxytryptamine |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
5-HT2C 5HTR2C |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
5HTR2C Conjugated |
| Short name: |
FITC Conjugated, 5HTR2C Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, 5HTR2C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5295 |
| Gene: |
HTR2C |
More about : HTR2C |
| Long gene name: |
5-hydroxytryptamine receptor 2C |
| Synonyms gene: |
HTR1C |
| Synonyms gene name: |
5-hydroxytryptamine (serotonin) receptor 2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled |
| Locus: |
Xq23 |
| Discovery year: |
1994-08-29 |
| Entrez gene record: |
3358 |
| Pubmed identfication: |
7895773 |
| RefSeq identity: |
NM_000868 |
| Classification: |
5-hydroxytryptamine receptors, G protein-coupled |
| Havana BLAST/BLAT: |
OTTHUMG00000022226 |
| Locus Specific Databases: |
Mental Retardation database LRG_1009 |