| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
5HTR2C |
| Specificity: |
This antibody reacts specifically with 5HTR2C |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human 5HTR2C |
| Gene ID: |
3358 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
5-HT), G-protein-coupled receptors, Jul 2008], RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims, This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, [provided by RefSeq, a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, thus modulating serotonergic neurotransmission in the central nervous system, where genomically encoded adenosine residues are converted to inosines, which activate phospholipase C and D signaling pathways, Serotonin (5-hydroxytryptamine |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
5-HT2C 5HTR2C |
| Also known as: |
5HTR2C Polyclonal Antibody |
| Other name: |
Anti-5HTR2C Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
5HTR2C |
| Short name: |
Anti-5HTR2C (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-5HTR2C (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
5295 |
| Gene: |
HTR2C |
More about : HTR2C |
| Long gene name: |
5-hydroxytryptamine receptor 2C |
| Synonyms gene: |
HTR1C |
| Synonyms gene name: |
5-hydroxytryptamine (serotonin) receptor 2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled |
| Locus: |
Xq23 |
| Discovery year: |
1994-08-29 |
| Entrez gene record: |
3358 |
| Pubmed identfication: |
7895773 |
| RefSeq identity: |
NM_000868 |
| Classification: |
5-hydroxytryptamine receptors, G protein-coupled |
| Havana BLAST/BLAT: |
OTTHUMG00000022226 |
| Locus Specific Databases: |
Mental Retardation database LRG_1009 |