| Catalog number: | bs-2912R-Cy5.5 |
|---|---|
| Price: | 263 € |
| Supplier: | Bioss Primary Unconjugated Antibodies |
| Product name: | MAP1A/MAP1B LC3 A/B Antibody, Cy5.5 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy5, 5 Conjugated, MAP1A/MAP1B LC3 A/B Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Cy5, 5, 5, Cy5 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | MAP1A/MAP1B LC3 A/B |
| Specificity: | This is a highly specific antibody against MAP1A/MAP1B LC3 A/B |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen_range: | 20-70/121 |
| Subcellular location: | Cell membrane, Cytoplasm |
| Source: | KLH conjugated synthetic peptide derived from human MAP1A/MAP1B LC3 B |
| Gene ID number: | 81631, 84557 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | A disruption to the autophagic process is now associated with the progression of several cancers, LC3, LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), This process of internal cellular turn-over is called autophagy (self-eating), a ubiquitin-like modifier protein, and is facilitated by a pathway of around 16 interacting proteins in the human, called autophagosomes, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, neurodegenerative disorders and cardiac pathologies, respectively, termed LC3-I and LC3-II, where LC3 is widely employed as a marker for autophagy, which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 675nm/694nm |
| Properties: | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: | MAP1A/MAP1B LC3 A/B Conjugated |
| Short name: | Conjugated, MAP1A/MAP1B LC3 A/B Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | 5, Cy5 |
| Alternative name: | cyanine 5, 5 coupled, MAP1A/MAP1B LC3 A/B (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 6835 |
| Gene: | MAP1A | More about : MAP1A |
| Long gene name: | microtubule associated protein 1A |
| Synonyms gene: | MAP1L |
| Locus: | 15q15, 3 |
| Discovery year: | 1992-07-09 |
| GenBank acession: | U38292 |
| Entrez gene record: | 4130 |
| Pubmed identfication: | 7806212 7629894 |
| RefSeq identity: | NM_002373 |
| Havana BLAST/BLAT: | OTTHUMG00000059756 |
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