| Long name: |
MAP1A/MAP1B LC3 A/B Antibody |
| Also known as: |
MAP1A/MAP1B LC3 A/B Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MAP1A/MAP1B LC3 A/B |
| Specificity: |
This is a highly specific antibody against MAP1A/MAP1B LC3 A/B |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
20-70/121 |
| Subcellular location: |
Cell membrane, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAP1A/MAP1B LC3 B |
| Gene ID number: |
81631, 84557 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A disruption to the autophagic process is now associated with the progression of several cancers, LC3, LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), This process of internal cellular turn-over is called autophagy (self-eating), a ubiquitin-like modifier protein, and is facilitated by a pathway of around 16 interacting proteins in the human, called autophagosomes, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, neurodegenerative disorders and cardiac pathologies, respectively, termed LC3-I and LC3-II, where LC3 is widely employed as a marker for autophagy, which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Autophagy related protein LC3 A, Autophagy related protein LC3 B, Autophagy related ubiquitin like modier LC3 A, Autophagy related ubiquitin like modier LC3 B, LC3, MAP1 light chain 3 like protein 1, MAP1 light chain 3 like protein 2, MAP1A/1B light chain 3 A, MAP1A/1B light chain 3 B, MAP1A/1BLC3, MAP1A/MAP1B LC3 A, MAP1A/MAP1B LC3 B, MAP1ALC3, MAP1BLC3, MAP1LC3A, MAP1LC3B, Microtubule associated protein 1 light chain 3 alpha, Microtubule associated protein 1 light chain 3 beta, Microtubule associated proteins 1A/1B light chain 3, Microtubule associated proteins 1A/1B light chain 3A, Microtubule associated proteins 1A/1B light chain 3B, MAP LC3 beta, microtubule-associated proteins 1A/1B light chain 3 beta 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MAP1A/MAP1B LC3 A/B |
| Short name: |
MAP1A/MAP1B LC3 A/B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MAP1A/MAP1B LC3 A/B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6835 |
| Gene: |
MAP1A |
More about : MAP1A |
| Long gene name: |
microtubule associated protein 1A |
| Synonyms gene: |
MAP1L |
| Locus: |
15q15, 3 |
| Discovery year: |
1992-07-09 |
| GenBank acession: |
U38292 |
| Entrez gene record: |
4130 |
| Pubmed identfication: |
7806212 7629894 |
| RefSeq identity: |
NM_002373 |
| Havana BLAST/BLAT: |
OTTHUMG00000059756 |