MEK6 Antibody, Cy5 Conjugated

Catalog number:	bs-2911R-Cy5 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	MEK6 Antibody, Cy5 Conjugated
Quantity:	100ul
Related search:	mapk kinase gene mek mapkmkk protein activation mitogenactivated regulation

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Long name:	Cy5 Conjugated, MEK6 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	5, Cy5
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	MEK6
Specificity:	This is a highly specific antibody against MEK6
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	270-320/334
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human MEK6
Gene ID number:	5608
Swiss Prot:	P52564
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Acts also as a regulator for melanocytes dendricity, Especially, Has a role in osteoclast differentiation through NF-kappa-B transactivation by TNFSF11, MAP2K3/MKK3 and MAP2K6/MKK6 are both essential for the activation of MAPK11 and MAPK13 induced by environmental stress, MAP2K6/MKK6 also phosphorylates and activates PAK6, MAP2K6/MKK6 mediates apoptotic cell death in thymocytes, MAP3K6/MKK6 mediates phosphorylation of STAT4 through MAPK14 activation, MAPK12, MAPK13 and MAPK14 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses, Nuclear targets of p38 MAP kinase include the transcription factors ATF2 and ELK1, The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors, The pathway is also crucial for IL-6-induced SOCS3 expression and down-regulation of IL-6-mediated gene induction, With MAP3K3/MKK3, Within the p38 MAPK signal transduction pathway, and for IFNG-dependent gene transcription, and in endochondral ossification and since SOX9 is another likely downstream target of the p38 MAPK pathway, and is therefore required for STAT4 activation and STAT4-regulated gene expression in response to IL-12 stimulation, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, through the modulation of Rho family GTPases, whereas MAP2K6/MKK6 is the major MAPK11 activator in response to TNF, Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	625, 650nm/670nm
Synonyms:	MEK6 MKK6 SAPKK3 MAPKK6
Properties:	Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	MEK6 Conjugated
Short name:	Conjugated, MEK6 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy5
Alternative name:	cyanine 5 coupled, MEK6 (Antibody to)
Alternative technique:	antibodies
Identity:	6846
Gene:	MAP2K6 | More about : MAP2K6
Long gene name:	mitogen-activated protein kinase kinase 6
Synonyms gene:	PRKMK6
Synonyms name:	kinase 6 (MAP kinase kinase 6) , mitogen-activated, protein kinase
Locus:	17q24, 3
Discovery year:	1997-11-11
GenBank acession:	U39064
Entrez gene record:	5608
Pubmed identfication:	8621675
RefSeq identity:	NM_002758
Classification:	Mitogen-activated protein kinase kinases
Havana BLAST/BLAT:	OTTHUMG00000180311

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