LATS1 Antibody, Biotin Conjugated

Catalog number:	bs-2904R-Biotin Buy Now
Price:	688 €
Supplier:	acr
Product name:	LATS1 Antibody, Biotin Conjugated
Quantity:	0,2 ml
Related search:	lats antibody gene biotin kinase protein large year

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Long name:	Biotin Conjugated, LATS1 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	LATS1
Specificity:	This is a highly specific antibody against LATS1
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic peptide derived from human LATS1
Gene ID number:	9113
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Biochemical and genetic data suggest a role as a tumor suppressor, In addition, The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, The protein is phosphorylated in a cell-cycle dependent manner, This is supported by studies in knockout mice showing development of soft-tissue sarcomas, [provided by RefSeq], indicating a role as a negative regulator of CDC2/cyclin A, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments, suggesting potential negative regulation through interference with complex formation via intramolecular binding, the C-terminal kinase domain binds to its own N-terminal region, with late prophase phosphorylation remaining through metaphase, The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	WARTS
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	LATS1 Conjugated
Short name:	Conjugated, LATS1 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, LATS1 (Antibody to)
Alternative technique:	antibodies
Identity:	6514
Gene:	LATS1 | More about : LATS1
Long gene name:	large tumor suppressor kinase 1
Synonyms gene name:	Drosophila) homolog 1 LATS, LATS (large tumor suppressor, homolog 1 (Drosophila) , large tumor suppressor
Locus:	6q25, 1
Discovery year:	1999-02-18
GenBank acession:	AF104413
Entrez gene record:	9113
Pubmed identfication:	9988268 15122335
RefSeq identity:	NM_004690
Havana BLAST/BLAT:	OTTHUMG00000016437

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