| Catalog number: | bs-2904R-A555 |
|---|---|
| Price: | 265 € |
| Supplier: | MBS Polyclonals |
| Product name: | LATS1 Antibody, ALEXA FLUOR 555 |
| Quantity: | 0.06 ml |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, LATS1 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-LATS1 PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | LATS1 |
| Specificity: | This is a highly specific antibody against LATS1 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LATS1 |
| Gene ID Number: | 9113 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Biochemical and genetic data suggest a role as a tumor suppressor, In addition, The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, The protein is phosphorylated in a cell-cycle dependent manner, This is supported by studies in knockout mice showing development of soft-tissue sarcomas, [provided by RefSeq], indicating a role as a negative regulator of CDC2/cyclin A, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments, suggesting potential negative regulation through interference with complex formation via intramolecular binding, the C-terminal kinase domain binds to its own N-terminal region, with late prophase phosphorylation remaining through metaphase, The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Synonyms: | WARTS |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | LATS1 |
| Short name: | LATS1 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, LATS1 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 6514 |
| Gene: | LATS1 | More about : LATS1 |
| Long gene name: | large tumor suppressor kinase 1 |
| Synonyms gene name: | Drosophila) homolog 1 LATS, LATS (large tumor suppressor, homolog 1 (Drosophila) , large tumor suppressor |
| Locus: | 6q25, 1 |
| Discovery year: | 1999-02-18 |
| GenBank acession: | AF104413 |
| Entrez gene record: | 9113 |
| Pubmed identfication: | 9988268 15122335 |
| RefSeq identity: | NM_004690 |
| Havana BLAST/BLAT: | OTTHUMG00000016437 |
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