| Catalog number: | bs-2898R-Cy3 |
|---|---|
| Price: | 558 € |
| Supplier: | acr |
| Product name: | NEMO Antibody, Cy3 Conjugated |
| Quantity: | 0,1 mg |
| Related search: |
| Long name: | Cy3 Conjugated, NEMO Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | cy3 conjugation kit |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | NEMO |
| Specificity: | This is a highly specific antibody against NEMO |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen_range: | 370-419/419 |
| Subcellular location: | Nucleus, Cytoplasm |
| Source: | KLH conjugated synthetic peptide derived from human NEMO |
| Gene ID number: | 8517 |
| Swiss Prot: | Q9Y6K9 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Also considered to be a mediator for TAX activation of NF-kappa-B, Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity, Essential for viral activation of IRF3, However, Involved in TLR3- and IFIH1-mediated antiviral innate response, Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly, this function requires 'Lys-27'-linked polyubiquitination, Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 512, 550nm/570, 615nm |
| Synonyms: | IKK-gamma NEMO Fip3p FIP-3 FIP3 ZC2HC9 |
| Properties: | 1 of the NEMO Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | NEMO Conjugated |
| Short name: | Conjugated, NEMO Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy3 |
| Alternative name: | cyanine 3 coupled, NEMO (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 5961 |
| Gene: | IKBKG | More about : IKBKG |
| Long gene name: | inhibitor of nuclear factor kappa B kinase subunit gamma |
| Synonyms gene: | IP2 IP1 |
| Synonyms gene name: | incontinentia pigmenti inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma |
| Locus: | Xq28 |
| Discovery year: | 1998-09-30 |
| GenBank acession: | AF074382 |
| Entrez gene record: | 8517 |
| Pubmed identfication: | 9751060 10087442 11590134 |
| RefSeq identity: | NM_003639 |
| Classification: | Zinc fingers C2HC-type |
| Havana BLAST/BLAT: | OTTHUMG00000024234 |
| Locus Specific Databases: | IKBKGbase: Mutation registry for Nemo deficiency Mental Retardation database LRG_70 |
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