| Long name: |
ALEXA FLUOR 647 Conjugated, Integrin alpha 2bPolyclonal Antibody |
| Also known as: |
Anti-Integrin alpha 2b/CD41 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Integrin alpha 2b/CD41 |
| Specificity: |
This is a highly specific antibody against Integrin alpha 2b/CD41 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
370-420/1033 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b |
| Gene ID Number: |
16399 |
| Swiss Prot: |
Q9QUM0 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen, It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain, It recognizes the sequence R-G-D in a wide array of ligands, This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin, Integrin alpha-IIb/beta-3 is a receptor for fibronectin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
AI172977, CD41B, GPalpha IIb, GpIIb, Integrin alpha-IIb, Itga2b, Platelet membrane glycoprotein IIb, alphaIIb, CD41 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Integrin alpha 2bAntibody, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Integrin alpha 2bAntibody |
| Short name: |
Integrin alpha 2bAntibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Integrin a 2bAntibody |
| Alternative technique: |
antibodies |