| Long name: |
Integrin alpha 2bPrimary Polyclonal Antibody |
| Also known as: |
Integrin alpha 2bPAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Integrin alpha 2b/CD41 |
| Specificity: |
This is a highly specific antibody against Integrin alpha 2b/CD41 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
370-420/1033 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b |
| Gene ID number: |
16399 |
| Swiss Prot: |
Q9QUM0 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen, It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain, It recognizes the sequence R-G-D in a wide array of ligands, This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin, Integrin alpha-IIb/beta-3 is a receptor for fibronectin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AI172977, CD41B, GPalpha IIb, GpIIb, Integrin alpha-IIb, Itga2b, Platelet membrane glycoprotein IIb, alphaIIb, CD41 |
| Gene target: |
Integrin alpha 2bAntibody |
| Short name: |
Integrin alpha 2bAntibody |
| Alternative name: |
Integrin a 2bAntibody |
| Alternative technique: |
antibodies |