| Long name: |
ALEXA FLUOR 488 Conjugated, c-Ros Polyclonal Antibody |
| Also known as: |
Anti-c-Ros PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
c-Ros |
| Specificity: |
This is a highly specific antibody against c-Ros |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
2300-2345/2347 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human c-Ros |
| Gene ID Number: |
6098 |
| Swiss Prot: |
P08922 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
IRS1 and PLCG2, MAPK1, MAPK3, May activate other downstream signaling proteins including AKT1, May activate several downstream signaling pathways related to cell differentiation, May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth, Mediates the phosphorylation and the activation of VAV3, Mediates the phosphorylation of PTPN11, a guanine nucleotide exchange factor regulating cell morphology, an activator of this pathway, growth and survival including the PI3 kinase-mTOR signaling pathway, proliferation, Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
MCF3 ROS c-ros-1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the c-Ros Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
c-Ros |
| Short name: |
c-Ros Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, c-Ros (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10261 |
| Gene: |
ROS1 |
More about : ROS1 |
| Long gene name: |
ROS proto-oncogene 1, receptor tyrosine kinase |
| Synonyms gene name: |
receptor tyrosine kinase , v-ros avian UR2 sarcoma virus oncogene homolog 1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) c-ros oncogene 1 |
| Locus: |
6q22, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M13599 |
| Entrez gene record: |
6098 |
| Pubmed identfication: |
1611909 |
| Classification: |
Fibronectin type III domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000016188 |
| Locus Specific Databases: |
LRG_997 |