| Long name: |
IL4R Primary Polyclonal Antibody |
| Also known as: |
IL4R PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
IL4R |
| Specificity: |
This is a highly specific antibody against IL4R |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
200-232/825 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IL4R |
| Gene ID number: |
3566 |
| Swiss Prot: |
P24394 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Couples to the JAK1/2/3-STAT6 pathway, IRS1/IRS2, In certain cell types, Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells, The IL4 response is involved in promoting Th2 differentiation, The IL4/IL13 responses are involved in regulating IgE production and, can signal through activation of insulin receptor substrates, chemokine and mucus production at sites of allergic inflammation, Receptor for both interleukin 4 and interleukin 13 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
582J2, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, IL4R, IL4RA, Interleukin-4 receptor subunit alpha, 1, CD124 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IL4R |
| Short name: |
IL4R Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
interleukin 4 receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD124 and IL-4RA and IL4RA, Extracellular, IL4R and IDBG-21808 and ENSG00000077238 and 3566, IL4R and IDBG-638778 and ENSBTAG00000001602 and 404154, Il4ra and IDBG-209275 and ENSMUSG00000030748 and 16190, insulin receptor substrate binding, this GO :0002532 and production of molecular mediator involved in inflammatory response and biological process this GO :0004896 and cytokine receptor activity and molecular function this GO :0004913 and interleukin-4 receptor activity and molecular function this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030728 and ovulation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035771 and interleukin-4-mediated signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042832 and defense response to protozoan and biological process this GO :0043032 and positive regulation of macrophage activation and biological process this GO :0043235 and receptor complex and cellular component this GO :0043560 and insulin receptor substrate binding and molecular function this GO :0043627 and response to estrogen and biological process this GO :0045087 and innate immune response and biological process this GO :0045626 and negative regulation of T-helper 1 cell differentiation and biological process this GO :0045630 and positive regulation of T-helper 2 cell differentiation and biological process this GO :0090197 and positive regulation of chemokine secretion and biological process, this GO :0004896 : cytokine receptor activity, this GO :0004896 : cytokine receptor activity and also this GO :0004913 : interleukin-4 receptor activity and also this GO :0005057 : receptor signaling protein activity and also this GO :0005515 : protein binding and also this GO :0043560 : insulin receptor substrate binding, this GO :0004913 : interleukin-4 receptor activity, this GO :0005057 : receptor signaling protein activity, this GO :0005515 : protein binding, this GO :0043560 : insulin receptor substrate binding, interleukin 4 receptor |
| Identity: |
6015 |
| Gene: |
IL4R |
More about : IL4R |
| Long gene name: |
interleukin 4 receptor |
| Synonyms: |
CD124 |
| Synonyms name: |
interleukin 13 receptor |
| Locus: |
16p12, 1 |
| Discovery year: |
1990-07-06 |
| GenBank acession: |
X52425 |
| Entrez gene record: |
3566 |
| Pubmed identfication: |
1679753 |
| Classification: |
CD molecules Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000097015 |