| Long name: |
ALEXA FLUOR 647 Conjugated, AVEN Polyclonal Antibody |
| Also known as: |
Anti-AVEN PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AVEN |
| Specificity: |
This is a highly specific antibody against AVEN |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AVEN |
| Gene ID Number: |
57099 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
AVEN is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9, Disruption of this process has been implicated in a variety of diseases such as cancer, Higher levels of AVEN mRNA are seen in patients with acute leukemia than in control patients, It is thought that AVEN functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and removal of damaged cells, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that AVEN impedes Apaf-1-mediated caspase activation, suggesting that AVEN may be useful as a prognostic indicator in leukemia patients, tissue homeostasis, Apoptosis plays a major role in normal organism development |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PDCD12 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the AVEN Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
AVEN |
| Short name: |
AVEN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, caspase activation inhibitor (Antibody to), apoptosis |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AVEN and IDBG-5324 and ENSG00000169857 and 57099, AVEN and IDBG-646114 and ENSBTAG00000044029 and 512666, Aven and IDBG-196731 and ENSMUSG00000003604 and 74268, Plasma membranes, caspase activation inhibitor, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0006915 and apoptotic process and biological process this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, apoptosis |
| Identity: |
13509 |
| Gene: |
AVEN |
More about : AVEN |
| Long gene name: |
apoptosis and caspase activation inhibitor |
| Synonyms name: |
cell death regulator aven programmed cell death 12 |
| Locus: |
15q14 |
| Discovery year: |
2002-09-17 |
| GenBank acession: |
AF283508 |
| Entrez gene record: |
57099 |
| Pubmed identfication: |
10949025 |
| RefSeq identity: |
NM_020371 |
| Havana BLAST/BLAT: |
OTTHUMG00000129371 |