| Long name: |
ALEXA FLUOR 350 Conjugated, APG7 Polyclonal Antibody |
| Also known as: |
Anti-APG7 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APG7 |
| Specificity: |
This is a highly specific antibody against APG7 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-50/70 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATG7 |
| Gene ID Number: |
10533 |
| Swiss Prot: |
O95352 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine, Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes, Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress, Plays also a key role in the maintenance of axonal homeostasis, Required for autophagic death induced by caspase-8 inhibition, Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production, as well as in adipose differentiation, the formation of Paneth cell granules, the maintenance of hematopoietic stem cells, the prevention of axonal degeneration, E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
GSA7 DKFZp434N0735 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
APG7 |
| Short name: |
APG7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, APG7 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16935 |
| Gene: |
ATG7 |
More about : ATG7 |
| Long gene name: |
autophagy related 7 |
| Synonyms gene: |
APG7L |
| Synonyms gene name: |
APG7 autophagy 7-like (S, cerevisiae) , cerevisiae) ATG7 autophagy related 7 homolog (S |
| Synonyms name: |
ubiquitin-activating enzyme E1-like protein |
| Locus: |
3p25, 3 |
| Discovery year: |
2003-11-20 |
| GenBank acession: |
AF094516 |
| Entrez gene record: |
10533 |
| Pubmed identfication: |
10233149 |
| RefSeq identity: |
NM_006395 |
| Classification: |
Ubiquitin like modifier activating enzymes Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000129740 |