| Long name: |
FITC Conjugated, NCR3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NCR3 |
| Specificity: |
This is a highly specific antibody against NCR3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
95-135/201 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human NCR3 |
| Gene ID number: |
259197 |
| Swiss Prot: |
O14931 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, and inducing NK cells to release TNFA and IFNG, both through killing those DCs that did not properly acquire a mature phenotype, which promotes DC maturation, Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
1C7 NKp30 CD337 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NCR3 Conjugated |
| Short name: |
FITC Conjugated, NCR3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, natural cytotoxicity triggering receptor 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
NCR3 and IDBG-634145 and ENSBTAG00000018343 and 513769, NCR3 and IDBG-78112 and ENSG00000204475 and 259197, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0008037 and cell recognition and biological process this GO :0045954 and positive regulation of natural killer cell mediated cytotoxicity and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, natural cytotoxicity triggering receptor 3 |
| Identity: |
19077 |
| Gene: |
NCR3 |
More about : NCR3 |
| Long gene name: |
natural cytotoxicity triggering receptor 3 |
| Synonyms gene: |
LY117 |
| Synonyms gene name: |
lymphocyte antigen 117 |
| Locus: |
6p21, 33 |
| Discovery year: |
2002-08-05 |
| GenBank acession: |
AB055881 |
| Entrez gene record: |
259197 |
| Pubmed identfication: |
8824804 11782277 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031123 |