| Long name: |
NCR3 Primary Polyclonal Antibody |
| Also known as: |
NCR3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
NCR3 |
| Specificity: |
This is a highly specific antibody against NCR3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
95-135/201 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NCR3 |
| Gene ID number: |
259197 |
| Swiss Prot: |
O14931 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, and inducing NK cells to release TNFA and IFNG, both through killing those DCs that did not properly acquire a mature phenotype, which promotes DC maturation, Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Activating natural killer receptor p30, CD337, LY117, MALS, NCR3, NK-p30, NKp30, Natural cytotoxicity triggering receptor 3, Natural killer cell p30-related protein, 1C7 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NCR3 |
| Short name: |
NCR3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
natural cytotoxicity triggering receptor 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
NCR3 and IDBG-634145 and ENSBTAG00000018343 and 513769, NCR3 and IDBG-78112 and ENSG00000204475 and 259197, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0008037 and cell recognition and biological process this GO :0045954 and positive regulation of natural killer cell mediated cytotoxicity and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, natural cytotoxicity triggering receptor 3 |
| Identity: |
19077 |
| Gene: |
NCR3 |
More about : NCR3 |
| Long gene name: |
natural cytotoxicity triggering receptor 3 |
| Synonyms gene: |
LY117 |
| Synonyms gene name: |
lymphocyte antigen 117 |
| Synonyms: |
1C7 NKp30 CD337 |
| Locus: |
6p21, 33 |
| Discovery year: |
2002-08-05 |
| GenBank acession: |
AB055881 |
| Entrez gene record: |
259197 |
| Pubmed identfication: |
8824804 11782277 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031123 |