| Long name: |
Biotin Conjugated, PXR Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PXR |
| Specificity: |
This is a highly specific antibody against PXR |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
80-130/434 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human PXR |
| Gene ID number: |
8856 |
| Swiss Prot: |
O75469 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Activated by naturally occurring steroids, Activated by the antibiotic rifampicin and various plant metabolites, Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes, Response to specific ligands is species-specific, Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, and isoflavones, colupulone, drugs and endogenous compounds, guggulipid, such as hyperforin, such as pregnenolone and progesterone, Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
ONR1 PXR BXR SXR PAR2 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PXR Conjugated |
| Short name: |
Conjugated, PXR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, PXR (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7968 |
| Gene: |
NR1I2 |
More about : NR1I2 |
| Long gene name: |
nuclear receptor subfamily 1 group I member 2 |
| Synonyms gene name: |
group I, member 2 , nuclear receptor subfamily 1 |
| Synonyms name: |
pregnane X receptor orphan nuclear receptor PXR |
| Locus: |
3q13, 33 |
| Discovery year: |
1999-04-23 |
| GenBank acession: |
AF061056 |
| Entrez gene record: |
8856 |
| Pubmed identfication: |
9727070 9770465 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000159400 |