Smad3 (Ser423) Antibody, ALEXA FLUOR 647

Catalog number:	bs-2225R-A647 Buy Now
Price:	663 €
Supplier:	MBS Polyclonals_1
Product name:	Smad3 (Ser423) Antibody, ALEXA FLUOR 647
Quantity:	10 Blots
Related search:	smad alexa ser fluor antibody antibodies conjugated beta tgf alternative madh

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Long name:	ALEXA FLUOR 647 Conjugated, Smad3 (Ser423) Polyclonal Antibody
Also known as:	Anti-Smad3 Ser423 PAb ALEXA FLUOR 647
Category:	Conjugated Primary Antibodies
Conjugated with:	647, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Smad3 Ser423
Specificity:	This is a highly specific antibody against Smad3 Ser423
Modification:	Phosphorylation
Modification Site:	Ser423
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human Smad3 around the phosphorylation site of Ser423
Gene ID Number:	4088
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	(Smad4) that functions via its interaction to the various Smads, (Smad6 and 7), 5, Activated Smad3 oligomerizes with Smad4 upon TGF beta stimulation and translocates as a complex into the nucleus, Phosphorylation of the two TGF beta dependent serines 423 and 425 in the C terminus of Smad3 is critical for Smad3 transcriptional activity and TGF beta signaling, The Smad family is divided into three subclasses: receptor regulated Smads, activin/TGF beta receptor regulated (Smad2 and 3) or BMP receptor regulated (Smad 1, allowing its binding to DNA and transcription factors, and 8), and the inhibitory Smads, differentiation and development, the common partner, Smad3 is a 50 kDa member of a family of proteins that act as key mediators of TGF beta superfamily signaling in cell proliferation
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	650nm/665nm
Synonyms:	HSPC193, JV15 2, JV152, MAD mothers against decapentaplegic Drosophila homolog 3, MAD3, MADH 3, MADH3, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3, SMA and MAD related protein 3, SMAD, SMAD 3, SMAD-3, SMAD3_HUMAN, Smad3 phospho S423, hMAD 3, hSMAD3, p-Smad3 Ser423, Smad3 phospho Ser423
Properties:	ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Smad3 (Ser423) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 647, Alexa Fluor
Gene target:	Smad3 (Ser423)
Short name:	Smad3 (Ser423) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 647
Alternative name:	ALEXA FLUOR 647, SMAD family member 3 (Ser423) (Antibody to)
Alternative technique:	antibodies

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