| Long name: |
PE Conjugated, OST-beta Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
PE |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OST-beta |
| Specificity: |
This is a highly specific antibody against OST-beta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human OST-beta |
| Gene ID number: |
123264 |
| Tested applications: |
FCM |
| Recommended dilutions: |
FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor), OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane, OST Beta is present at highest levels in ileum, This genetic regulation suggests that in response to changes in intracellular bile acid levels, Though widely expressed, bile acids adjust the rate of their own efflux from enterocytes, kidney and adrenal gland, liver, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus, testis, The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
480, 565nm/578nm |
| Synonyms: |
OST KIAA0115 OST48 WBP1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
OST-beta PE Conjugated |
| Short name: |
PE Conjugated, OST-beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
PE |
| Alternative name: |
peroxidase coupled, OST-b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2728 |
| Gene: |
DDOST |
More about : DDOST |
| Long gene name: |
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit |
| Synonyms gene name: |
dolichyl-diphosphooligosaccharide-protein glycosyltransferase |
| Synonyms name: |
oligosaccharyltransferase subunit 48 advanced glycation end-product receptor 1 |
| Locus: |
1p36, 12 |
| Discovery year: |
1997-12-23 |
| GenBank acession: |
D29643 |
| Entrez gene record: |
1650 |
| Pubmed identfication: |
9367678 |
| RefSeq identity: |
NM_005216 |
| Classification: |
Oligosaccharyltransferase complex subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000002844 |