| Long name: |
ALEXA FLUOR 555 Conjugated, OST-beta Polyclonal Antibody |
| Also known as: |
Anti-OST-beta PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OST-beta |
| Specificity: |
This is a highly specific antibody against OST-beta |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OST-beta |
| Gene ID Number: |
123264 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor), OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane, OST Beta is present at highest levels in ileum, This genetic regulation suggests that in response to changes in intracellular bile acid levels, Though widely expressed, bile acids adjust the rate of their own efflux from enterocytes, kidney and adrenal gland, liver, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus, testis, The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
OST KIAA0115 OST48 WBP1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
OST-beta |
| Short name: |
OST-beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, OST-b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2728 |
| Gene: |
DDOST |
More about : DDOST |
| Long gene name: |
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit |
| Synonyms gene name: |
dolichyl-diphosphooligosaccharide-protein glycosyltransferase |
| Synonyms name: |
oligosaccharyltransferase subunit 48 advanced glycation end-product receptor 1 |
| Locus: |
1p36, 12 |
| Discovery year: |
1997-12-23 |
| GenBank acession: |
D29643 |
| Entrez gene record: |
1650 |
| Pubmed identfication: |
9367678 |
| RefSeq identity: |
NM_005216 |
| Classification: |
Oligosaccharyltransferase complex subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000002844 |