| Long name: |
ALEXA FLUOR 647 Conjugated, ABI1 Polyclonal Antibody |
| Also known as: |
Anti-ABI1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ABI1 |
| Specificity: |
This is a highly specific antibody against ABI1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
140-190/508 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ABI1 |
| Gene ID Number: |
10006 |
| Swiss Prot: |
Q8IZP0 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex, In brain, In vitro, Involved in cytoskeletal reorganization and EGFR signaling, May play a role in regulation of EGF-induced Erk pathway activation, Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level, Regulates ABL1/c-Abl-mediated phosphorylation of ENAH, Together with EPS8 participates in transduction of signals from Ras to Rac, a trimeric complex of ABI1, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons, May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
E3B1 ABI-1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ABI1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
ABI1 |
| Short name: |
ABI1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, ABI1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11320 |
| Gene: |
ABI1 |
More about : ABI1 |
| Long gene name: |
abl interactor 1 |
| Synonyms gene: |
SSH3BP1 |
| Synonyms gene name: |
spectrin SH3 domain binding protein 1 abl-interactor 1 |
| Locus: |
10p12, 1 |
| Discovery year: |
1999-05-17 |
| GenBank acession: |
U87166 |
| Entrez gene record: |
10006 |
| Pubmed identfication: |
9593709 9010225 |
| RefSeq identity: |
NM_005470 |
| Havana BLAST/BLAT: |
OTTHUMG00000017848 |