| Long name: |
HRP Conjugated, ZW10 peptide Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ZW10 peptide |
| Specificity: |
This is a highly specific antibody against ZW10 peptide |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from mouse ZW10 |
| Gene ID number: |
9183 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Depletion from human cells demonstrates that the ZW10 complex is essential for stable binding of a Mad1-Mad2 complex to unattached kinetochores, In mitotic human cells ZW10 resides in a complex with Rod and Zwilch, It is part of the MIS12 complex, The encoded protein binds to centromeres during the prophase, This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division, Thus, ZW10 functions as a linker between the core structural elements of the outer kinetochore and components that catalyze generation of the mitotic checkpoint-derived ", Zwint-1, Zwint-1 is critical for recruiting ZW10 to unattached kinetochores, and early anaphase cell division stages and to kinetochore microtubules during metaphase, inhibitor, is part of a separate complex of structural kinetochore components including Mis12 and Ndc80-Hec1, metaphase, whereas another ZW10 partner, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis, The mitotic checkpoint ensures that chromosomes are divided equally between daughter cells and is a primary mechanism preventing the chromosome instability often seen in aneuploid human tumors, stop anaphase" |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
KNTC1AP |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Description: |
, The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs, The shortest peptides are dipeptides, These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), and unbranched synthetic peptide chains, consisting of 2 amino acids joined by a single peptide bond, continuous, followed by tripeptides, or in continue produced for custom peptide synthesis projects, tetra peptides, till polypeptides that are long, Peptides short amino acid chains or epitopes or blocking antagonists |
| Gene target: |
ZW10 peptide Conjugated |
| Short name: |
Conjugated, ZW10 peptide Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, peptides, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, ZW10 short protein sequence (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13194 |
| Gene: |
ZW10 |
More about : ZW10 |
| Long gene name: |
zw10 kinetochore protein |
| Synonyms gene name: |
ZW10 (Drosophila) homolog, centromere/kinetochore protein ZW10, homolog (Drosophila) , kinetochore associated |
| Locus: |
11q23, 2 |
| Discovery year: |
1999-05-11 |
| GenBank acession: |
U54996 |
| Entrez gene record: |
9183 |
| Pubmed identfication: |
9298984 |
| RefSeq identity: |
NM_004724 |
| Havana BLAST/BLAT: |
OTTHUMG00000168190 |