| Long name: |
Thrombin heavy chain Primary Polyclonal Antibody |
| Also known as: |
Thrombin heavy chain PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Thrombin heavy chain |
| Specificity: |
This is a highly specific antibody against Thrombin heavy chain |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Thrombin heavy chain |
| Gene ID number: |
2147 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Glycosaminoglycan binding to exosite II of thrombin plays a major role in switching off the procoagulant functions of thrombin by mediating its irreversible inhibition by circulating serpins and by its binding to the endothelial cell surface receptor thrombomodulin, The ability of thrombin to specifically recognize a wide range of substrates derives from interactions which occur outside of the active site of thrombin, Thrombin possesses two anion binding exosites which mediate many of its interactions with cofactors and substrates, and although many structures of thrombin have been solved, few such interactions have been described in molecular detail, Thrombin is the final protease in the blood coagulation cascade and serves both pro- and anticoagulant functions through the cleavage of several targets |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Cf-2, Cf2, Coagulation factor II, Coagulation factor II precursor, F 2, F2, F2, FII, Factor II, Factor-II, PT, Prothrombin, THRB, THRB_HUMAN, Thrombin, Thrombin heavy chain, coagulation factor II thrombin, prothrombin, prothrombin B-chain, serine protease, coagulation factor II |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Thrombin heavy chain |
| Short name: |
Thrombin heavy chain Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Thrombin heavy epitope (Antibody to) |
| Alternative technique: |
antibodies |