| Long name: |
Cy5, 5 Conjugated, SCN2A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SCN2A |
| Specificity: |
This is a highly specific antibody against SCN2A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SCN2A |
| Gene ID number: |
6326 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It is heterogeneously expressed in the brain, Several alternatively spliced transcript variants of this gene have been described, They are responsible for the generation and propagation of action potentials in neurons and muscle, This gene encodes one member of the sodium channel alpha subunit gene family, and mutations in this gene have been linked to several seizure disorders, but the full-length nature of some of these variants has not been determined, Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
Nav1, 2 HBSCII HBSCI |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
SCN2A Conjugated |
| Short name: |
Conjugated, SCN2A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
alpha subunit (Antibody to), classification II, cyanine 5, voltage-gated, 5 coupled, sodium channel |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BFIC3 and BFIS3 and BFNIS and EIEE11 and HBA and HBSCI and HBSCII and Na(v)1, BT, Plasma membranes, SCN2A and IDBG-74003 and ENSG00000136531 and 6326, Scn2a1 and IDBG-174901 and ENSMUSG00000075318 and 110876, alpha subunit, protein binding, this GO :0001518 and voltage-gated sodium channel complex and cellular component this GO :0005216 and ion channel activity and molecular function this GO :0005248 and voltage-gated sodium channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006811 and ion transport and biological process this GO :0006814 and sodium ion transport and biological process this GO :0007399 and nervous system development and biological process this GO :0008627 and intrinsic apoptotic signaling pathway in response to osmotic stress and biological process this GO :0014704 and intercalated disc and cellular component this GO :0016020 and membrane and cellular component this GO :0019228 and neuronal action potential and biological process this GO :0030315 and T-tubule and cellular component this GO :0030424 and axon and cellular component this GO :0031226 and intrinsic component of plasma membrane and cellular component this GO :0033268 and node of Ranvier and cellular component this GO :0033270 and paranode region of axon and cellular component this GO :0034706 and sodium channel complex and cellular component this GO :0034765 and regulation of ion transmembrane transport and biological process this GO :0035725 and sodium ion transmembrane transport and biological process this GO :0042552 and myelination and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0055085 and transmembrane transport and biological process this GO :0086010 and membrane depolarization during action potential and biological process, this GO :0005216 : ion channel activity, this GO :0005216 : ion channel activity and also this GO :0005248 : voltage-gated sodium channel activity and also this GO :0005515 : protein binding, this GO :0005248 : voltage-gated sodium channel activity, this GO :0005515 : protein binding, type II, voltage-gated, 2 and NAC2 and Nav1, 2 and SCN2A1 and SCN2A2, 99915 and IDBG-641113 and ENSBTAG00000038180 and 539718, sodium channel |
| Identity: |
10588 |
| Gene: |
SCN2A |
More about : SCN2A |
| Long gene name: |
sodium voltage-gated channel alpha subunit 2 |
| Synonyms gene: |
SCN2A1 SCN2A2 |
| Synonyms gene name: |
alpha 1 polypeptide sodium channel, alpha 2 polypeptide sodium channel, alpha subunit sodium channel, sodium channel, type II, type II, type II, type II alpha subunit , voltage gated, voltage-gated, voltage-gated, voltage-gated |
| Locus: |
2q24, 3 |
| Discovery year: |
1992-08-07 |
| GenBank acession: |
AB208888 |
| Entrez gene record: |
6326 |
| Pubmed identfication: |
1317301 16382098 |
| RefSeq identity: |
NM_021007 |
| Classification: |
Sodium voltage-gated channel alpha subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000044172 |