| Long name: |
FITC Conjugated, MKP-2/DUSP4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MKP-2/DUSP4 |
| Specificity: |
This is a highly specific antibody against MKP-2/DUSP4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human MKP-2 |
| Gene ID number: |
1846 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, ERK2 and JNK, In addition, SAPK/JNK, These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues, They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, This gene product inactivates ERK1, Two alternatively spliced transcript variants, and different modes of inducibility of their expression by extracellular stimuli, and is localized in the nucleus, different tissue distribution and subcellular localization, encoding distinct isoforms, have been observed for this gene, is expressed in a variety of tissues, multiple polyadenylation sites have been reported, p38), which is associated with cellular proliferation and differentiation, DUSP4 is a member of the dual specificity protein phosphatase subfamily |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
HVH2 MKP-2 TYP |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MKP-2/DUSP4 Conjugated |
| Short name: |
FITC Conjugated, MKP-2/DUSP4 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, MKP-2/DUSP4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3070 |
| Gene: |
DUSP4 |
More about : DUSP4 |
| Long gene name: |
dual specificity phosphatase 4 |
| Synonyms name: |
VH1 homologous phosphatase 2 MAP kinase phosphatase 2 |
| Locus: |
8p12 |
| Discovery year: |
1994-12-14 |
| GenBank acession: |
U21108 |
| Entrez gene record: |
1846 |
| Pubmed identfication: |
7535768 9205128 |
| RefSeq identity: |
NM_001394 |
| Classification: |
MAP kinase phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000133395 |