| Long name: |
HRP Conjugated, IL1RAP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IL1RAP |
| Specificity: |
This is a highly specific antibody against IL1RAP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
300-335/570 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human IL1RAP/IL1R3 |
| Gene ID number: |
3556 |
| Swiss Prot: |
Q9NPH3 |
| Tested applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways, Coreceptor with IL1R1 in the IL-1 signaling system, Does not bind to interleukin-1 alone, MYD88, Recruits TOLLIP to the signaling complex, Secreted forms (isoforms 2 and 3) associate with secreted ligand-bound IL1R2 and increase the affinity of secreted IL1R2 for IL1B, Signaling involves the recruitment of adapter molecules such as TOLLIP, The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits, binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors, Coreceptor for IL1RL2 in the IL-36 signaling system (By similarity) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
IL-1RAcP IL1R3 C3orf13 |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
IL1RAP Conjugated |
| Short name: |
Conjugated, IL1RAP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, interleukin 1 receptor accessory protein (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C3orf13 and IL-1RAcP and IL1R3, Extracellular, IL1RAP and IDBG-634437 and ENSBTAG00000013205 and 539334, IL1RAP and IDBG-69682 and ENSG00000196083 and 3556, Il1rap and IDBG-150439 and ENSMUSG00000022514 and 16180, protein binding, this GO :0004871 and signal transducer activity and molecular function this GO :0004908 and interleukin-1 receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0016020 and membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0042094 and interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0004908 : interleukin-1 receptor activity and also this GO :0005515 : protein binding, this GO :0004908 : interleukin-1 receptor activity, this GO :0005515 : protein binding, interleukin 1 receptor accessory protein |
| Identity: |
5995 |
| Gene: |
IL1RAP |
More about : IL1RAP |
| Long gene name: |
interleukin 1 receptor accessory protein |
| Locus: |
3q28 |
| Discovery year: |
1997-10-09 |
| GenBank acession: |
AB006537 |
| Entrez gene record: |
3556 |
| Pubmed identfication: |
9479509 9065432 |
| RefSeq identity: |
NM_001167929 |
| Classification: |
Immunoglobulin like domain containing Interleukin receptors TIR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000156211 |