| Long name: |
Gastrin receptor/CCKBR Antibody |
| Also known as: |
Gastrin receptor/CCKBR Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Gastrin receptor/GASR/CCKBR |
| Specificity: |
This is a highly specific antibody against Gastrin receptor/GASR/CCKBR |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
300-350/447 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Gastrin receptor |
| Gene ID number: |
887 |
| Swiss Prot: |
P32239 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism, The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system, analgesia, and neuroleptic activity, arousal, Receptor for gastrin and cholecystokinin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CCK-B, CCK-B receptor, CCK-BR, CCK2-R, CCK2R, CCKBR, CCKRB, Cholecystokinin-2 receptor, Gastrin/cholecystokinin type B receptor, GASR |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
Gastrin receptor/CCKBR |
| Short name: |
Gastrin receptor/CCKBR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Gastrin receptor/cholecystokinin B receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
1-phosphatidylinositol-3-kinase regulator activity, CCK-B and CCK2R and GASR, CCKBR and IDBG-28586 and ENSG00000110148 and 887, CCKBR and IDBG-634214 and ENSBTAG00000005236 and 281665, Cckbr and IDBG-204676 and ENSMUSG00000030898 and 12426, Plasma membranes, this GO :0001696 and gastric acid secretion and biological process this GO :0004435 and phosphatidylinositol phospholipase C activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004951 and cholecystokinin receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007200 and phospholipase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007586 and digestion and biological process this GO :0007600 and sensory perception and biological process this GO :0007631 and feeding behavior and biological process this GO :0008152 and metabolic process and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0015054 and gastrin receptor activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0031741 and type B gastrin/cholecystokinin receptor binding and molecular function this GO :0038188 and cholecystokinin signaling pathway and biological process this GO :0043551 and regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0046935 and 1-phosphatidylinositol-3-kinase regulator activity and molecular function this GO :0048565 and digestive tract development and biological process this GO :0048732 and gland development and biological process, this GO :0004435 : phosphatidylinositol phospholipase C activity, this GO :0004435 : phosphatidylinositol phospholipase C activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004951 : cholecystokinin receptor activity and also this GO :0005515 : protein binding and also this GO :0015054 : gastrin receptor activity and also this GO :0031741 : type B gastrin/cholecystokinin receptor binding and also this GO :0046935 : 1-phosphatidylinositol-3-kinase regulator activity, this GO :0004930 : G-protein coupled receptor activity, this GO :0004951 : cholecystokinin receptor activity, this GO :0005515 : protein binding, this GO :0015054 : gastrin receptor activity, this GO :0031741 : type B gastrin/cholecystokinin receptor binding, this GO :0046935 : 1-phosphatidylinositol-3-kinase regulator activity, cholecystokinin B receptor |
| Identity: |
1571 |
| Gene: |
CCKBR |
More about : CCKBR |
| Long gene name: |
cholecystokinin B receptor |
| Locus: |
11p15, 4 |
| Discovery year: |
1993-07-13 |
| GenBank acession: |
D13305 |
| Entrez gene record: |
887 |
| Pubmed identfication: |
1280419 |
| RefSeq identity: |
NM_176875 |
| Classification: |
Cholecystokinin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133380 |