| Long name: |
HRP Conjugated, CBX4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CBX4 |
| Specificity: |
This is a highly specific antibody against CBX4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
415-445/560 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human CBX4 |
| Gene ID number: |
8535 |
| Swiss Prot: |
O00257 |
| Tested applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, Involved in the sumoylation of HNRNPK, Monosumoylates ZNF131, PcG PRC1 complex acts via chromatin remodeling and modification of histones, a complex class required to maintain the transcriptionally repressive state of many genes, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression, including Hox genes, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility, throughout development, E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
hPC2 PC2 NBP16 |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
CBX4 Conjugated |
| Short name: |
Conjugated, CBX4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, chromobox homolog 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CBX4 and IDBG-642715 and ENSBTAG00000009782 and, CBX4 and IDBG-71254 and ENSG00000141582 and 8535, Cbx4 and IDBG-214671 and ENSMUSG00000039989 and 12418, DNA-templated and biological process this GO :0016568 and chromatin modification and biological process this GO :0016604 and nuclear body and cellular component this GO :0016607 and nuclear speck and cellular component this GO :0016874 and ligase activity and molecular function this GO :0016925 and protein sumoylation and biological process this GO :0019899 and enzyme binding and molecular function this GO :0031519 and PcG protein complex and cellular component this GO :0032183 and SUMO binding and molecular function this GO :0035064 and methylated histone binding and molecular function this GO :0035102 and PRC1 complex and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0051219 and phosphoprotein binding and molecular function, NBP16 and PC2, nuclei, phosphoprotein binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0003682 and chromatin binding and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0003727 and single-stranded RNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0006351 and transcription, this GO :0003682 : chromatin binding, this GO :0003682 : chromatin binding and also this GO :0003714 : transcription corepressor activity and also this GO :0003727 : single-stranded RNA binding and also this GO :0005515 : protein binding and also this GO :0016874 : ligase activity and also this GO :0019899 : enzyme binding and also this GO :0032183 : SUMO binding and also this GO :0035064 : methylated histone binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0051219 : phosphoprotein binding, this GO :0003714 : transcription corepressor activity, this GO :0003727 : single-stranded RNA binding, this GO :0005515 : protein binding, this GO :0016874 : ligase activity, this GO :0019899 : enzyme binding, this GO :0032183 : SUMO binding, this GO :0035064 : methylated histone binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0051219 : phosphoprotein binding, chromobox homolog 4 |
| Identity: |
1554 |
| Gene: |
CBX4 |
More about : CBX4 |
| Long gene name: |
chromobox 4 |
| Synonyms gene name: |
chromobox homolog 4 (Drosophila Pc class) chromobox homolog 4 |
| Synonyms name: |
NS5ATP1-binding protein 16 Pc class 2 homolog (Drosophila) |
| Locus: |
17q25, 3 |
| Discovery year: |
1998-10-20 |
| GenBank acession: |
AF013956 |
| Entrez gene record: |
8535 |
| Pubmed identfication: |
9315667 |
| RefSeq identity: |
NM_003655 |
| Classification: |
Chromobox family |
| Havana BLAST/BLAT: |
OTTHUMG00000150415 |