| Long name: |
ALEXA FLUOR 647 Conjugated, DAPK1/2 Polyclonal Antibody |
| Also known as: |
Anti-DAPK1/2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DAPK1/2 |
| Specificity: |
This is a highly specific antibody against DAPK1/2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
325-365/370 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DAPK2 |
| Gene ID Number: |
23604 |
| Swiss Prot: |
Q9UIK4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells, Isoform 2 is not regulated by calmodulin, It can induce membrane blebbing and autophagic cell death, It can phosphorylate MYL9, May play a role in granulocytic maturation, Regulates both type I apoptotic and type II autophagic cell deaths signal, The former is caspase-dependent, and autophagy, apoptosis, depending on the cellular setting, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles, Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
DAPK |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the DAPK1/2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
DAPK1/2 |
| Short name: |
DAPK1/2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, death-associated protein kinase 1/2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DAPK, DAPK1 and IDBG-636344 and ENSBTAG00000000738 and 540873, DAPK1 and IDBG-74918 and ENSG00000196730 and 1612, Dapk1 and IDBG-159357 and ENSMUSG00000021559 and 69635, Plasma membranes, alcohol group as acceptor, alcohol group as acceptor and also this GO :0042802 : identical protein binding, alcohol group as acceptor and molecular function this GO :0017148 and negative regulation of translation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000310 and regulation of N-methyl-D-aspartate selective glutamate receptor activity and biological process, this GO :0003824 and catalytic activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004683 and calmodulin-dependent protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0009103 and lipopolysaccharide biosynthetic process and biological process this GO :0010506 and regulation of autophagy and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004683 : calmodulin-dependent protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004683 : calmodulin-dependent protein kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005516 : calmodulin binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0016773 : phosphotransferase activity, this GO :0042802 : identical protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0016773 : phosphotransferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, death-associated protein kinase 1 |
| Identity: |
2674 |
| Gene: |
DAPK1 |
More about : DAPK1 |
| Long gene name: |
death associated protein kinase 1 |
| Synonyms gene name: |
death-associated protein kinase 1 |
| Locus: |
9q21, 33 |
| Discovery year: |
1995-04-27 |
| GenBank acession: |
X76104 |
| Entrez gene record: |
1612 |
| Pubmed identfication: |
8530096 |
| RefSeq identity: |
NM_004938 |
| Classification: |
Death associated protein kinases Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020150 |