| Long name: |
DAPK1/2 Primary Polyclonal Antibody |
| Also known as: |
DAPK1/2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DAPK1/2 |
| Specificity: |
This is a highly specific antibody against DAPK1/2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
325-365/370 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DAPK2 |
| Gene ID number: |
23604 |
| Swiss Prot: |
Q9UIK4 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells, Isoform 2 is not regulated by calmodulin, It can induce membrane blebbing and autophagic cell death, It can phosphorylate MYL9, May play a role in granulocytic maturation, Regulates both type I apoptotic and type II autophagic cell deaths signal, The former is caspase-dependent, and autophagy, apoptosis, depending on the cellular setting, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles, Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DAP kinase 2, DAP-kinase-related protein 1, DAPK2, DRP-1, Death-associated protein kinase 2, DRP1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DAPK1/2 |
| Short name: |
DAPK1/2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
death-associated protein kinase 1/2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DAPK, DAPK1 and IDBG-636344 and ENSBTAG00000000738 and 540873, DAPK1 and IDBG-74918 and ENSG00000196730 and 1612, Dapk1 and IDBG-159357 and ENSMUSG00000021559 and 69635, Plasma membranes, alcohol group as acceptor, alcohol group as acceptor and also this GO :0042802 : identical protein binding, alcohol group as acceptor and molecular function this GO :0017148 and negative regulation of translation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000310 and regulation of N-methyl-D-aspartate selective glutamate receptor activity and biological process, this GO :0003824 and catalytic activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004683 and calmodulin-dependent protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0009103 and lipopolysaccharide biosynthetic process and biological process this GO :0010506 and regulation of autophagy and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004683 : calmodulin-dependent protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004683 : calmodulin-dependent protein kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005516 : calmodulin binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0016773 : phosphotransferase activity, this GO :0042802 : identical protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0016773 : phosphotransferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, death-associated protein kinase 1 |
| Identity: |
2674 |
| Gene: |
DAPK1 |
More about : DAPK1 |
| Long gene name: |
death associated protein kinase 1 |
| Synonyms gene name: |
death-associated protein kinase 1 |
| Synonyms: |
DAPK |
| Locus: |
9q21, 33 |
| Discovery year: |
1995-04-27 |
| GenBank acession: |
X76104 |
| Entrez gene record: |
1612 |
| Pubmed identfication: |
8530096 |
| RefSeq identity: |
NM_004938 |
| Classification: |
Death associated protein kinases Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020150 |