| Long name: |
CCR8 Primary Polyclonal Antibody |
| Also known as: |
CCR8 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CCR8 |
| Specificity: |
This is a highly specific antibody against CCR8 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from mouse CCR-8 |
| Gene ID number: |
1237 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CCR8 expression has been reported in spleen and thymus, CCR8 is also believed to be alternative coreceptor with CD4 for HIV-1 infection, Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites, I-309, More specifically, Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis, This gene is located at the chemokine receptor gene cluster region, This receptor protein preferentially expresses in the thymus, and T cells, and at lower levels in peripheral blood leukocytes, monocytes, natural killer cells, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues, thymus activation regulated cytokine (TARC) and macrophage inflammatory protein 1 beta (MIP1 beta) have been identified as ligands of this receptor, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors, This gene encodes a member of the beta chemokine receptor family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C-C CKR-8, C-C chemokine receptor type 8, CC-CKR-8, CC-chemokine receptor CHEMR1, CCR8, CCR8_MOUSE, CD_antigen=CDw198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, GPRCY6, TER1, C-C chemokine receptor 8, CCR-8, GPR-CY6 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CCR8 |
| Short name: |
CCR8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-C motif) receptor 8 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, C-C chemokine receptor activity, CC-CKR-8 and CCR-8 and CDw198 and CKRL1 and CMKBR8 and CMKBRL2 and CY6 and GPRCY6 and TER1, CCR8 and IDBG-26700 and ENSG00000179934 and 1237, Ccr8 and IDBG-205018 and ENSMUSG00000042262 and 12776, Plasma membranes, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0005515 : protein binding and also this GO :0015026 : coreceptor activity and also this GO :0016493 : C-C chemokine receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0005515 : protein binding, this GO :0015026 : coreceptor activity, this GO :0016493 : C-C chemokine receptor activity, 30825 and IDBG-647797 and ENSBTAG00000015483 and 407772, chemokine (C-C motif) receptor 8 |
| Identity: |
1609 |
| Gene: |
CCR8 |
More about : CCR8 |
| Long gene name: |
C-C motif chemokine receptor 8 |
| Synonyms gene: |
CMKBRL2 CMKBR8 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 8 |
| Synonyms: |
CY6 TER1 CKR-L1 GPR-CY6 CDw198 |
| Locus: |
3p22, 1 |
| Discovery year: |
1997-04-21 |
| GenBank acession: |
D49919 |
| Entrez gene record: |
1237 |
| Pubmed identfication: |
8816377 8886020 |
| RefSeq identity: |
NM_005201 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000131290 |