| Long name: |
Biotin Conjugated, CXCR2/CD182 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CXCR2/CD182 |
| Specificity: |
This is a highly specific antibody against CXCR2/CD182 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
316-350/360 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human CXCR2 |
| Gene ID number: |
3579 |
| Swiss Prot: |
P25025 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also binds with high affinity to CXCL3, Binding of IL-8 to the receptor causes activation of neutrophils, Binds to IL-8 with high affinity, GRO/MGSA and NAP-2, This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system, Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CMKAR2 CD182 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CXCR2/CD182 Conjugated |
| Short name: |
Conjugated, CXCR2/CD182 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, chemokine (C-X-C motif) receptor 2/CD182 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD182 and CDw128b and CMKAR2 and IL8R2 and IL8RA and IL8RB, CXCR2 and IDBG-80804 and ENSG00000180871 and 3579, Cell surfaces, Cxcr2 and IDBG-166395 and ENSMUSG00000026180 and 12765, interleukin-8 binding, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0004918 and interleukin-8 receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007200 and phospholipase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0019959 and interleukin-8 binding and molecular function this GO :0030593 and neutrophil chemotaxis and biological process this GO :0031623 and receptor internalization and biological process this GO :0038112 and interleukin-8-mediated signaling pathway and biological process this GO :0042119 and neutrophil activation and biological process this GO :0042629 and mast cell granule and cellular component this GO :0045087 and innate immune response and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0004918 : interleukin-8 receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0005515 : protein binding and also this GO :0016494 : C-X-C chemokine receptor activity and also this GO :0019959 : interleukin-8 binding, this GO :0004918 : interleukin-8 receptor activity, this GO :0004930 : G-protein coupled receptor activity, this GO :0005515 : protein binding, this GO :0016494 : C-X-C chemokine receptor activity, this GO :0019959 : interleukin-8 binding, chemokine (C-X-C motif) receptor 2 |
| Identity: |
6027 |
| Gene: |
CXCR2 |
More about : CXCR2 |
| Long gene name: |
C-X-C motif chemokine receptor 2 |
| Synonyms gene: |
IL8RB |
| Synonyms gene name: |
beta chemokine (C-X-C motif) receptor 2 , interleukin 8 receptor |
| Locus: |
2q35 |
| Discovery year: |
1991-08-19 |
| GenBank acession: |
U11869 |
| Entrez gene record: |
3579 |
| Pubmed identfication: |
1427896 |
| RefSeq identity: |
NM_001557 |
| Classification: |
CD molecules C-X-C motif chemokine receptors Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133107 |