| Long name: |
CXCR2/CD182 Primary Polyclonal Antibody |
| Also known as: |
CXCR2/CD182 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CXCR2/CD182 |
| Specificity: |
This is a highly specific antibody against CXCR2/CD182 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
316-350/360 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CXCR2 |
| Gene ID number: |
3579 |
| Swiss Prot: |
P25025 |
| Tested Applications: |
IF(ICC), IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also binds with high affinity to CXCL3, Binding of IL-8 to the receptor causes activation of neutrophils, Binds to IL-8 with high affinity, GRO/MGSA and NAP-2, This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system, Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C-X-C chemokine receptor type 2, CDw128b, CMKAR2, CXC-R2, CXCR-2, CXCR2, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8 receptor type 2, IL-8R B, IL8R2, IL8RA, IL8RB, CD182 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CXCR2/CD182 |
| Short name: |
CXCR2/CD182 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-X-C motif) receptor 2/CD182 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD182 and CDw128b and CMKAR2 and IL8R2 and IL8RA and IL8RB, CXCR2 and IDBG-80804 and ENSG00000180871 and 3579, Cell surfaces, Cxcr2 and IDBG-166395 and ENSMUSG00000026180 and 12765, interleukin-8 binding, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0004918 and interleukin-8 receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007200 and phospholipase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0019959 and interleukin-8 binding and molecular function this GO :0030593 and neutrophil chemotaxis and biological process this GO :0031623 and receptor internalization and biological process this GO :0038112 and interleukin-8-mediated signaling pathway and biological process this GO :0042119 and neutrophil activation and biological process this GO :0042629 and mast cell granule and cellular component this GO :0045087 and innate immune response and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0004918 : interleukin-8 receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0005515 : protein binding and also this GO :0016494 : C-X-C chemokine receptor activity and also this GO :0019959 : interleukin-8 binding, this GO :0004918 : interleukin-8 receptor activity, this GO :0004930 : G-protein coupled receptor activity, this GO :0005515 : protein binding, this GO :0016494 : C-X-C chemokine receptor activity, this GO :0019959 : interleukin-8 binding, chemokine (C-X-C motif) receptor 2 |
| Identity: |
6027 |
| Gene: |
CXCR2 |
More about : CXCR2 |
| Long gene name: |
C-X-C motif chemokine receptor 2 |
| Synonyms gene: |
IL8RB |
| Synonyms gene name: |
beta chemokine (C-X-C motif) receptor 2 , interleukin 8 receptor |
| Synonyms: |
CMKAR2 CD182 |
| Locus: |
2q35 |
| Discovery year: |
1991-08-19 |
| GenBank acession: |
U11869 |
| Entrez gene record: |
3579 |
| Pubmed identfication: |
1427896 |
| RefSeq identity: |
NM_001557 |
| Classification: |
CD molecules C-X-C motif chemokine receptors Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133107 |