| Long name: |
ALEXA FLUOR 647 Conjugated, PDCD4 Polyclonal Antibody |
| Also known as: |
Anti-PDCD4 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PDCD4 |
| Specificity: |
This is a highly specific antibody against PDCD4 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
30-80/469 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDCD4 |
| Gene ID Number: |
27250 |
| Swiss Prot: |
Q53EL6 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binds RNA (By similarity), Down-regulates the expression of MAP4K1, Inhibits the helicase activity of EIF4A, Inhibits tumor promoter-induced neoplastic transformation, MAPK85 activation and consequent JUN-dependent transcription, May excert its function by hindering the interaction between EIF4A1 and EIF4G, May play a role in apoptosis, Modulates the activation of JUN kinase, Tumor suppressor, namely, thus inhibiting events important in driving invasion, Inhibits translation initiation and cap-dependent translation |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
H731 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the PDCD4 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
PDCD4 |
| Short name: |
PDCD4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, programmed cellular death 4 (neoplastic transformation inhibitor) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process, PDCD4 and IDBG-639738 and ENSBTAG00000019434 and 506724, PDCD4 and IDBG-89535 and ENSG00000150593 and 100616113, Pdcd4 and IDBG-176913 and ENSMUSG00000024975 and 18569, nuclei, protein binding, this GO :0003723 and RNA binding and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007569 and cell aging and biological process this GO :0043508 and negative regulation of JUN kinase activity and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, this GO :0003723 : RNA binding, this GO :0003723 : RNA binding and also this GO :0005488 : binding and also this GO :0005515 : protein binding, this GO :0005488 : binding, this GO :0005515 : protein binding, 27250, programmed cell death 4 (neoplastic transformation inhibitor) |
| Identity: |
8763 |
| Gene: |
PDCD4 |
More about : PDCD4 |
| Long gene name: |
programmed cell death 4 |
| Synonyms gene name: |
programmed cell death 4 (neoplastic transformation inhibitor) |
| Synonyms name: |
nuclear antigen H731 |
| Locus: |
10q25, 2 |
| Discovery year: |
2000-05-10 |
| GenBank acession: |
U83908 |
| Entrez gene record: |
27250 |
| Pubmed identfication: |
9759869 |
| RefSeq identity: |
NM_014456 |
| Havana BLAST/BLAT: |
OTTHUMG00000019048 |