| Long name: |
ALEXA FLUOR 594 Conjugated, PDCD4 Polyclonal Antibody |
| Also known as: |
Anti-PDCD4 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PDCD4 |
| Specificity: |
This is a highly specific antibody against PDCD4 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
30-80/469 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDCD4 |
| Gene ID Number: |
27250 |
| Swiss Prot: |
Q53EL6 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binds RNA (By similarity), Down-regulates the expression of MAP4K1, Inhibits the helicase activity of EIF4A, Inhibits tumor promoter-induced neoplastic transformation, MAPK85 activation and consequent JUN-dependent transcription, May excert its function by hindering the interaction between EIF4A1 and EIF4G, May play a role in apoptosis, Modulates the activation of JUN kinase, Tumor suppressor, namely, thus inhibiting events important in driving invasion, Inhibits translation initiation and cap-dependent translation |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
H731 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
PDCD4 |
| Short name: |
PDCD4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, programmed cellular death 4 (neoplastic transformation inhibitor) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process, PDCD4 and IDBG-639738 and ENSBTAG00000019434 and 506724, PDCD4 and IDBG-89535 and ENSG00000150593 and 100616113, Pdcd4 and IDBG-176913 and ENSMUSG00000024975 and 18569, nuclei, protein binding, this GO :0003723 and RNA binding and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007569 and cell aging and biological process this GO :0043508 and negative regulation of JUN kinase activity and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, this GO :0003723 : RNA binding, this GO :0003723 : RNA binding and also this GO :0005488 : binding and also this GO :0005515 : protein binding, this GO :0005488 : binding, this GO :0005515 : protein binding, 27250, programmed cell death 4 (neoplastic transformation inhibitor) |
| Identity: |
8763 |
| Gene: |
PDCD4 |
More about : PDCD4 |
| Long gene name: |
programmed cell death 4 |
| Synonyms gene name: |
programmed cell death 4 (neoplastic transformation inhibitor) |
| Synonyms name: |
nuclear antigen H731 |
| Locus: |
10q25, 2 |
| Discovery year: |
2000-05-10 |
| GenBank acession: |
U83908 |
| Entrez gene record: |
27250 |
| Pubmed identfication: |
9759869 |
| RefSeq identity: |
NM_014456 |
| Havana BLAST/BLAT: |
OTTHUMG00000019048 |