| Long name: |
Cy5, 5 Conjugated, DTNBP1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DTNBP1 |
| Specificity: |
This is a highly specific antibody against DTNBP1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
130-180/351 |
| Subcellular location: |
Cytoplasm, Nucleus, Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human DTNBP1 |
| Gene ID number: |
84062 |
| Swiss Prot: |
Q96EV8 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function, In concert with the AP-3 complex, May modulate MAPK8 phosphorylation, May play a role in actin cytoskeleton reorganization and neurite outgrowth, Modulates prefrontal cortical activity via the dopamine/D2 pathway, Plays a role in synaptic vesicle trafficking and in neurotransmitter release, Plays a role in the regulation of cell surface exposure of DRD2, Regulates the expression of SYN1 through binding to its promoter, The BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), in association with SNARE proteins, is also proposed to be involved in neurite extension, modulating PI3-kinase-Akt signaling and influencing glutamatergic release, such as platelet dense granules and melanosomes, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals, Component of the BLOC-1 complex |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
Dysbindin My031 HPS7 DBND BLOC1S8 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
DTNBP1 Conjugated |
| Short name: |
Conjugated, DTNBP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, DTNBP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17328 |
| Gene: |
DTNBP1 |
More about : DTNBP1 |
| Long gene name: |
dystrobrevin binding protein 1 |
| Synonyms name: |
dysbindin-1 biogenesis of lysosomal organelles complex-1, subunit 8 |
| Locus: |
6p22, 3 |
| Discovery year: |
2002-01-15 |
| GenBank acession: |
AF394226 |
| Entrez gene record: |
84062 |
| Pubmed identfication: |
11316798 |
| RefSeq identity: |
NM_032122 |
| Classification: |
Biogenesis of lysosomal organelles complex 1 |
| Havana BLAST/BLAT: |
OTTHUMG00000014295 |
| Locus Specific Databases: |
LRG_588 |