| Catalog number: | bs-15472R-A488 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | HGD Antibody, ALEXA FLUOR 488 |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | ALEXA FLUOR 488 Conjugated, HGD Polyclonal Antibody |
|---|---|
| Also known as: | Anti-HGD PAb ALEXA FLUOR 488 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 488, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | HGD |
| Specificity: | This is a highly specific antibody against HGD |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HGD |
| Gene ID Number: | 3081 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), Expressed at high levels in kidney, HGD uses iron as a cofactor to catalyze the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid, an autosomal recessive disorder that is characterized by urine that turns dark on standing and alkalinization, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis, colon, liver, prostate and small intestine, HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 499nm/519nm |
| Synonyms: | HGO |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the HGD Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | HGD |
| Short name: | HGD Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 488 |
| Alternative name: | ALEXA FLUOR 488, HGD (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4892 |
| Gene: | HGD | More about : HGD |
| Long gene name: | homogentisate 1, 2-dioxygenase |
| Synonyms gene: | AKU |
| Synonyms gene name: | homogentisate 1, 2-dioxygenase (homogentisate oxidase) |
| Synonyms name: | homogentisate oxidase |
| Locus: | 3q13, 33 |
| Discovery year: | 1993-07-26 |
| Entrez gene record: | 3081 |
| Pubmed identfication: | 8188241 |
| Havana BLAST/BLAT: | OTTHUMG00000159441 |
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