| Catalog number: | bs-15472R |
|---|---|
| Price: | 333 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | HGD Antibody |
| Quantity: | 0.1ml |
| Other quantities: | 1 vial 521€ |
| Related search: |
| Long name: | HGD Primary Polyclonal Antibody |
|---|---|
| Also known as: | HGD PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | HGD |
| Specificity: | This is a highly specific antibody against HGD |
| Modification(s): | None |
| Modification site(s): | Unmodified antibody |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HGD |
| Gene ID number: | 3081 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), Expressed at high levels in kidney, HGD uses iron as a cofactor to catalyze the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid, an autosomal recessive disorder that is characterized by urine that turns dark on standing and alkalinization, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis, colon, liver, prostate and small intestine, HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | AKU, FLJ94126, HGD_HUMAN, HGO, Homogentisate 1, Homogentisate 1 2 dioxygenase, Homogentisate oxidase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase, hgd, 2-dioxygenase |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | HGD |
| Short name: | HGD Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | HGD (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4892 |
| Gene: | HGD | More about : HGD |
| Long gene name: | homogentisate 1, 2-dioxygenase |
| Synonyms gene: | AKU |
| Synonyms gene name: | homogentisate 1, 2-dioxygenase (homogentisate oxidase) |
| Synonyms: | HGO |
| Synonyms name: | homogentisate oxidase |
| Locus: | 3q13, 33 |
| Discovery year: | 1993-07-26 |
| Entrez gene record: | 3081 |
| Pubmed identfication: | 8188241 |
| Havana BLAST/BLAT: | OTTHUMG00000159441 |
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