| Catalog number: | bs-15406R |
|---|---|
| Price: | 333 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | Hamartin Antibody |
| Quantity: | 0.1ml |
| Other quantities: | 0.1mg 406€ 0.4 ml 406€ |
| Related search: |
| Long name: | Hamartin Primary Polyclonal Antibody |
|---|---|
| Also known as: | Hamartin PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | Hamartin |
| Specificity: | This is a highly specific antibody against Hamartin |
| Modification(s): | None |
| Modification site(s): | Unmodified antibody |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Hamartin |
| Gene ID number: | 7248 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion, Hamartin is present in most adult tissues with strong expression in brain, Tuberin and hamartin interact with each other forming a cystoplasmic complex, Two different genetic loci have been linked to TSC, and kidney, encodes a protein called hamartin, encodes a protein called tuberin and the other loci, heart, one of these loci, the tuberous sclerosis-2 gene (TSC2), tuberous sclerosis-1 gene (TSC1), Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | LAM, TSC, TSC1, TSC1_HUMAN, Tsc1 gene, Tuberous sclerosis 1, Tuberous sclerosis 1 protein, kiaa0243, Hamartin |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | Hamartin |
| Short name: | Hamartin Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | Hamartin (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 12362 |
| Gene: | TSC1 | More about : TSC1 |
| Long gene name: | tuberous sclerosis 1 |
| Synonyms gene: | TSC |
| Synonyms: | KIAA0243 LAM hamartin |
| Locus: | 9q34 |
| Discovery year: | 1986-01-01 |
| GenBank acession: | AF013168 |
| Pubmed identfication: | 9242607 10806479 |
| Havana BLAST/BLAT: | OTTHUMG00000020844 |
| Locus Specific Databases: | TSC Mutation Database Tuberous sclerosis database LRG_486 |
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