| Long name: |
ALEXA FLUOR 488 Conjugated, Hamartin Polyclonal Antibody |
| Also known as: |
Anti-Hamartin PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Hamartin |
| Specificity: |
This is a highly specific antibody against Hamartin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Hamartin |
| Gene ID Number: |
7248 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion, Hamartin is present in most adult tissues with strong expression in brain, Tuberin and hamartin interact with each other forming a cystoplasmic complex, Two different genetic loci have been linked to TSC, and kidney, encodes a protein called hamartin, encodes a protein called tuberin and the other loci, heart, one of these loci, the tuberous sclerosis-2 gene (TSC2), tuberous sclerosis-1 gene (TSC1), Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
KIAA0243 LAM hamartin |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Hamartin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Hamartin |
| Short name: |
Hamartin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Hamartin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12362 |
| Gene: |
TSC1 |
More about : TSC1 |
| Long gene name: |
tuberous sclerosis 1 |
| Synonyms gene: |
TSC |
| Locus: |
9q34 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AF013168 |
| Pubmed identfication: |
9242607 10806479 |
| Havana BLAST/BLAT: |
OTTHUMG00000020844 |
| Locus Specific Databases: |
TSC Mutation Database Tuberous sclerosis database LRG_486 |