| Long name: |
Biotin Conjugated, GPR161 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPR161 |
| Specificity: |
This is a highly specific antibody against GPR161 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
165-190/529 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GPR161 |
| Gene ID number: |
23432 |
| Swiss Prot: |
Q8N6U8 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In presence of SHH, Its ligand is unknown (By similarity), Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, it is removed from primary cilia and is internalized into recycling endosomes, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling, preventing its activity and allowing activation of the Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development, Key negative regulator of Shh signaling |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
RE2 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPR161 Conjugated |
| Short name: |
Conjugated, GPR161 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, GPR161 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23694 |
| Gene: |
GPR161 |
More about : GPR161 |
| Long gene name: |
G protein-coupled receptor 161 |
| Locus: |
1q24, 2 |
| Discovery year: |
2003-12-01 |
| GenBank acession: |
AF091890 |
| Entrez gene record: |
23432 |
| Pubmed identfication: |
11959142 |
| RefSeq identity: |
NM_007369 |
| Classification: |
Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000034651 |