| Long name: |
ALEXA FLUOR 594 Conjugated, NeuroD1 Polyclonal Antibody |
| Also known as: |
Anti-NeuroD1 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NeuroD1 |
| Specificity: |
This is a highly specific antibody against NeuroD1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-50/356 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NeuroD1 |
| Gene ID Number: |
4760 |
| Swiss Prot: |
Q13562 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Also required for dendrite morphogenesis and maintenance in the cerebellar cortex, Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity), Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A, Contributes to the regulation of several cell differentiation pathways, Together with PAX6 or SIX3, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, inner ear sensory neurons, is required for the regulation of amacrine cell fate specification, like those that promote the formation of early retinal ganglion cells, Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3' |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BETA2 BHF-1 NeuroD bHLHa3 MODY6 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
NeuroD1 |
| Short name: |
NeuroD1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, neuronal differentiation 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7762 |
| Gene: |
NEUROD1 |
More about : NEUROD1 |
| Long gene name: |
neuronal differentiation 1 |
| Synonyms gene: |
NEUROD |
| Synonyms gene name: |
neurogenic differentiation 1 |
| Synonyms name: |
beta-cell E-box transactivator 2 neurogenic helix-loop-helix protein NEUROD |
| Locus: |
2q31, 3 |
| Discovery year: |
1996-03-12 |
| GenBank acession: |
U50823 |
| Entrez gene record: |
4760 |
| Pubmed identfication: |
7754368 8786144 |
| RefSeq identity: |
NM_002500 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000132583 |