| Long name: |
Nck1/NCK alpha Primary Polyclonal Antibody |
| Also known as: |
Nck1/NCK alpha PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Nck1/NCK alpha |
| Specificity: |
This is a highly specific antibody against Nck1/NCK alpha |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Nck2 |
| Gene ID number: |
4690 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It is a common target for the action of different surface receptors, Like other SH2 containing proteins, Nck is associated with tyrosine autophosphorylated EGF or PDGF receptors via its SH2 domain, Nck is phosphorylated on tyrosine, Nck is widely expressed in various tissues and in cell lines from human, Overexpression of Nck leads to transformation of NIH 3T3 cells, Ras GTPase activating protein, and phospholipase Cg, and rat origins, and threonine residues in response to stimulation of EGF and PDGF in A431 and NIH 3T3 cells respectively, encoding one SH2 and three SH3 domains, murine, oncogenic protein, phosphatidylinositol 3 kinase, serine, the Src homology motifs found in nonreceptor tyrosine kinases, Nck is a highly conserved |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Cytoplasmic protein NCK1, MGC12668, Melanoma Nck protein, NCK 1, NCK tyrosine kinase, NCK1, NCKalpha, Nck adaptor protein 1, Non catalytic region of tyrosine kinase, SH2/SH3 adaptor protein NCK alpha, SH2/SH3 adaptor protein NCK alpha, NCK adaptor protein 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Nck1/NCK alpha |
| Short name: |
Nck1/NCK alpha Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NCK adaptor protein 1/NCK a (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7664 |
| Gene: |
NCK1 |
More about : NCK1 |
| Long gene name: |
NCK adaptor protein 1 |
| Synonyms gene: |
NCK |
| Synonyms: |
NCKalpha |
| Locus: |
3q22, 3 |
| Discovery year: |
1998-11-04 |
| GenBank acession: |
X17576 |
| Entrez gene record: |
4690 |
| Pubmed identfication: |
7806213 9737977 |
| RefSeq identity: |
NM_006153 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000159781 |