| Long name: |
HSP75/TRAP1 Primary Polyclonal Antibody |
| Also known as: |
HSP75/TRAP1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HSP75/TRAP1 |
| Specificity: |
This is a highly specific antibody against HSP75/TRAP1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
530-580/704 |
| Subcellular location: |
Mitochondrion |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HSP75 |
| Gene ID number: |
10131 |
| Swiss Prot: |
Q12931 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Involved in maintaining mitochondrial function and polarization, Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis, The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA, most likely through stabilization of mitochondrial complex I, Chaperone that expresses an ATPase activity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
HSP 75, HSP90L, Heat shock protein 75 kDa, TNFR-associated protein 1, TRAP-1, TRAP1, Tumor necrosis factor type 1 receptor-associated protein, mitochondrial, HSP75 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HSP75/TRAP1 |
| Short name: |
HSP75/TRAP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HSP75/tumor necrosis factor receptor-associated protein 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
HSP 75 and HSP75 and HSP90L and TRAP-1, TRAP1 and IDBG-12290 and ENSG00000126602 and 10131, TRAP1 and IDBG-636097 and ENSBTAG00000020109 and 514472, Trap1 and IDBG-129450 and ENSMUSG00000005981 and 68015, nuclei, this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005758 and mitochondrial intermembrane space and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0006457 and protein folding and biological process this GO :0006950 and response to stress and biological process this GO :0016020 and membrane and cellular component this GO :0044822 and poly(A) RNA binding and molecular function this GO :0051082 and unfolded protein binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :1901856 and negative regulation of cellular respiration and biological process this GO :1902176 and negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway and biological process, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0044822 : poly(A) RNA binding and also this GO :0051082 : unfolded protein binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0044822 : poly(A) RNA binding, this GO :0051082 : unfolded protein binding, unfolded protein binding, 101929751, TNF receptor-associated protein 1 |
| Identity: |
16264 |
| Gene: |
TRAP1 |
More about : TRAP1 |
| Long gene name: |
TNF receptor associated protein 1 |
| Synonyms gene name: |
TNF receptor-associated protein 1 |
| Synonyms: |
HSP75 HSP90L |
| Locus: |
16p13, 3 |
| Discovery year: |
2004-07-02 |
| GenBank acession: |
AF154108 |
| Entrez gene record: |
10131 |
| Pubmed identfication: |
10652318 7876093 |
| RefSeq identity: |
NM_016292 |
| Classification: |
Heat shock 90kDa proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000129427 |