| Long name: |
ALEXA FLUOR 647 Conjugated, IGFBP3 Polyclonal Antibody |
| Also known as: |
Anti-IGFBP3 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IGFBP3 |
| Specificity: |
This is a highly specific antibody against IGFBP3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
240-296/296 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IGFBP3 |
| Gene ID Number: |
3486 |
| Swiss Prot: |
P17936 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R, They alter the interaction of IGFs with their cell surface receptors, IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
IBP3 BP-53 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the IGFBP3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
IGFBP3 |
| Short name: |
IGFBP3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, insulin-like growth factor binding protein 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BP-53 and IBP3, IGFBP3 and IDBG-15809 and ENSG00000146674 and 3486, IGFBP3 and IDBG-633994 and ENSBTAG00000003994 and 282261, Igfbp3 and IDBG-148893 and ENSMUSG00000020427 and 16009, metal ion binding, nuclei, this GO :0001558 and regulation of cell growth and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0001968 and fibronectin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005520 and insulin-like growth factor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0008160 and protein tyrosine phosphatase activator activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0010906 and regulation of glucose metabolic process and biological process this GO :0014912 and negative regulation of smooth muscle cell migration and biological process this GO :0016942 and insulin-like growth factor binding protein complex and cellular component this GO :0031994 and insulin-like growth factor I binding and molecular function this GO :0040008 and regulation of growth and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043568 and positive regulation of insulin-like growth factor receptor signaling pathway and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0044342 and type B pancreatic cell proliferation and biological process this GO :0045663 and positive regulation of myoblast differentiation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001968 : fibronectin binding, this GO :0001968 : fibronectin binding and also this GO :0005515 : protein binding and also this GO :0005520 : insulin-like growth factor binding and also this GO :0008160 : protein tyrosine phosphatase activator activity and also this GO :0031994 : insulin-like growth factor I binding and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0005520 : insulin-like growth factor binding, this GO :0008160 : protein tyrosine phosphatase activator activity, this GO :0031994 : insulin-like growth factor I binding, this GO :0046872 : metal ion binding, insulin-like growth factor binding protein 3 |
| Identity: |
5472 |
| Gene: |
IGFBP3 |
More about : IGFBP3 |
| Long gene name: |
insulin like growth factor binding protein 3 |
| Synonyms gene name: |
insulin-like growth factor binding protein 3 |
| Synonyms name: |
growth hormone-dependent binding protein acid stable subunit of the 140 K IGF complex binding protein 53 binding protein 29 IGF-binding protein 3 |
| Locus: |
7p12, 3 |
| Discovery year: |
1991-07-09 |
| Entrez gene record: |
3486 |
| Pubmed identfication: |
1695633 |
| RefSeq identity: |
NM_001013398 |
| Classification: |
Insulin like growth factor binding proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000023769 |
| Locus Specific Databases: |
LRG_68 |