| Long name: |
ALEXA FLUOR 555 Conjugated, Claudin 18 Polyclonal Antibody |
| Also known as: |
Anti-Claudin 18 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Claudin 18 |
| Specificity: |
This is a highly specific antibody against Claudin 18 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Claudin 18 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Claudins, Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues (1), Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge (5), Occludin and Junction adhesion molecule (3), These proteins are important structural and functional components of tight junctions in paracellular transport (1, Three classes of proteins are known to localize to tight junctions, including the Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands (4), 2), Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions (6), The Claudin superfamily consists of many structurally related proteins in humans (1) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
Claudin 18 |
| Short name: |
Claudin 18 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, Claudin 18 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2039 |
| Gene: |
CLDN18 |
More about : CLDN18 |
| Long gene name: |
claudin 18 |
| Synonyms gene: |
SFTPJ |
| Synonyms gene name: |
surfactant associated protein J |
| Locus: |
3q22, 3 |
| Discovery year: |
2000-01-31 |
| GenBank acession: |
AF221069 AY102073 |
| Entrez gene record: |
51208 |
| RefSeq identity: |
NM_001002026 |
| Classification: |
Claudins |
| Havana BLAST/BLAT: |
OTTHUMG00000159762 |