| Long name: |
Biotin Conjugated, CILP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CILP |
| Specificity: |
The immunogen falls within the Cartilage intermediate layer protein 1 C2 region, This is a highly specific antibody against CILP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1085-1115/1184 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human CILP |
| Gene ID number: |
8483 |
| Swiss Prot: |
O75339 |
| Tested applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions, May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1, Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage, and inhibits ligand-induced IGF1R autophosphorylation, Probably plays a role in cartilage scaffolding |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
HsT18872 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CILP Conjugated |
| Short name: |
Conjugated, CILP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, CILP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1980 |
| Gene: |
CILP |
More about : CILP |
| Long gene name: |
cartilage intermediate layer protein |
| Synonyms gene name: |
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| Locus: |
15q22, 31 |
| Discovery year: |
1998-08-18 |
| GenBank acession: |
AY358904 |
| Entrez gene record: |
8483 |
| Pubmed identfication: |
9722584 9722583 |
| RefSeq identity: |
NM_003613 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133140 |