| Long name: |
CILP Primary Polyclonal Antibody |
| Also known as: |
CILP PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CILP |
| Specificity: |
The immunogen falls within the Cartilage intermediate layer protein 1 C2 region, This is a highly specific antibody against CILP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1085-1115/1184 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CILP |
| Gene ID number: |
8483 |
| Swiss Prot: |
O75339 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions, May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1, Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage, and inhibits ligand-induced IGF1R autophosphorylation, Probably plays a role in cartilage scaffolding |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CILP, Cartilage intermediate layer protein 1, Cartilage intermediate-layer protein, HsT18872, UNQ602/PRO1188, CILP-1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CILP |
| Short name: |
CILP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CILP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1980 |
| Gene: |
CILP |
More about : CILP |
| Long gene name: |
cartilage intermediate layer protein |
| Synonyms gene name: |
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| Synonyms: |
HsT18872 |
| Locus: |
15q22, 31 |
| Discovery year: |
1998-08-18 |
| GenBank acession: |
AY358904 |
| Entrez gene record: |
8483 |
| Pubmed identfication: |
9722584 9722583 |
| RefSeq identity: |
NM_003613 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133140 |