| Also known as: |
SOD1 / SOD |
| Other names: |
Cu/Zn superoxide dismutase, SOD, Superoxide dismutase 1, Superoxide dismutase [Cu-Zn], cystolic, epididymis secretory protein Li 44, hSod1, indophenoloxidase A, soluble, soluble, superoxide dismutase, superoxide dismutase 1, superoxide dismutase [Cu-Zn], superoxide dismutase [Cu-Zn], superoxide dismutase |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SOD1 |
| Gene name synonims: |
SOD |
| Other gene names: |
ALS, ALS1, HEL-S-44, IPOA, SOD, SOD1, hSod1, hSod1, homodimer, SOD1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
2F5 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Human (Homo sapiens), Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Bovine |
| Specificity and cross-reactivity: |
Does not cross react with immunoglobulins but does react weakly with Mn SOD, SOD Cu/Zn prevents oxygen-mediated free radical damage by catalyzing the dismutation of the toxic superoxide radical to molecular oxygen and hydrogen peroxide, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Superoxide dismutases are ubiquitous metalloproteins that destroy oxygen-mediated free radicals, The Cu/Zn form of SOD is utilized by most eukaryotic organisms, There are three forms of superoxide dismutase, This particular antibody might cross react with speacies outside of the listed ones, including the Fe, mitochondrial (Mn) and the copper/zinc binding (Cu/Zn) form, that are normally produced within the cells, which are toxic to biological systems, Recognizes copper/zinc superoxide dismutase (SOD) |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
Sourced in TCS, 1% BSA, 1% sodium azide and 0, PBS with 0 |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), IHC - Frozen), Immunohistochemistry (IHC - Paraffin |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 2F5] (IgG1) SOD1 / SOD |
| Short name: |
Mouse Monoclonal [clone 2F5] (IgG1) SOD1 / SOD Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Bos Taurus genes are available form the Bovine Genome database, Mouses, Bovine |
| Alternative name: |
soluble / antioxidant enzyme (Antibody to), Mouse monoclonal [clonality 2F5] (IgG1) to Bovine superoxide dismutase 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ALS and ALS1 and HEL-S-44 and homodimer and hSod1 and IPOA and SOD, SOD1 and IDBG-1609 and ENSG00000142168 and 6647, Sod1 and IDBG-174662 and ENSMUSG00000022982 and 20655, chaperone binding, nuclei, soluble, this GO :0000187 and activation of MAPK activity and biological process this GO :0000302 and response to reactive oxygen species and biological process this GO :0000303 and response to superoxide and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0001819 and positive regulation of cytokine production and biological process this GO :0001890 and placenta development and biological process this GO :0001895 and retina homeostasis and biological process this GO :0001975 and response to amphetamine and biological process this GO :0002262 and myeloid cell homeostasis and biological process this GO :0002576 and platelet degranulation and biological process this GO :0004784 and superoxide dismutase activity and molecular function this GO :0005507 and copper ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005758 and mitochondrial intermembrane space and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006749 and glutathione metabolic process and biological process this GO :0006801 and superoxide metabolic process and biological process this GO :0006879 and cellular iron ion homeostasis and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007566 and embryo implantation and biological process this GO :0007568 and aging and biological process this GO :0007569 and cell aging and biological process this GO :0007596 and blood coagulation and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0007626 and locomotory behavior and biological process this GO :0008089 and anterograde axon car this GO transport and biological process this GO :0008090 and retrograde axon car this GO transport and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0008219 and cell death and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009408 and response to heat and biological process this GO :0010033 and response to organic substance and biological process this GO :0019226 and transmission of nerve impulse and biological process this GO :0019430 and removal of superoxide radicals and biological process this GO :0019899 and enzyme binding and molecular function this GO :0030141 and secretory granule and cellular component this GO :0030168 and platelet activation and biological process this GO :0030346 and protein phosphatase 2B binding and molecular function this GO :0031012 and extracellular matrix and cellular component this GO :0031045 and dense core granule and cellular component this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0031667 and response to nutrient levels and biological process this GO :0032287 and peripheral nervous system myelin maintenance and biological process this GO :0032314 and regulation of Rac GTPase activity and biological process this GO :0032839 and dendrite cytoplasm and cellular component this GO :0032930 and positive regulation of superoxide anion generation and biological process this GO :0033081 and regulation of T cell differentiation in thymus and biological process this GO :0034465 and response to carbon monoxide and biological process this GO :0034599 and cellular response to oxidative stress and biological process this GO :0035865 and cellular response to potassium ion and biological process this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0042493 and response to drug and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042554 and superoxide anion generation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043234 and protein complex and cellular component this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045471 and response to ethanol and biological process this GO :0045541 and negative regulation of cholesterol biosynthetic process and biological process this GO :0045859 and regulation of protein kinase activity and biological process this GO :0046620 and regulation of organ growth and biological process this GO :0046677 and response to antibiotic and biological process this GO :0046688 and response to copper ion and biological process this GO :0046716 and muscle cell cellular homeostasis and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048365 and Rac GTPase binding and molecular function this GO :0048538 and thymus development and biological process this GO :0048678 and response to axon injury and biological process this GO :0050665 and hydrogen peroxide biosynthetic process and biological process this GO :0051087 and chaperone binding and molecular function this GO :0051881 and regulation of mitochondrial membrane potential and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0060047 and heart contraction and biological process this GO :0060052 and neurofilament cytoskeleton organization and biological process this GO :0060087 and relaxation of vascular smooth muscle and biological process this GO :0060088 and auditory receptor cell stereocilium organization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071276 and cellular response to cadmium ion and biological process this GO :0071318 and cellular response to ATP and biological process this GO :0072593 and reactive oxygen species metabolic process and biological process this GO :0097332 and response to antipsychotic drug and biological process this GO :1902177 and positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway and biological process, this GO :0004784 : superoxide dismutase activity, this GO :0004784 : superoxide dismutase activity and also this GO :0005507 : copper ion binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0019899 : enzyme binding and also this GO :0030346 : protein phosphatase 2B binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046872 : metal ion binding and also this GO :0048365 : Rac GTPase binding and also this GO :0051087 : chaperone binding, this GO :0005507 : copper ion binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0019899 : enzyme binding, this GO :0030346 : protein phosphatase 2B binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0046872 : metal ion binding, this GO :0048365 : Rac GTPase binding, this GO :0051087 : chaperone binding, superoxide dismutase 1 |
| Identity: |
11179 |
| Gene: |
SOD1 |
More about : SOD1 |
| Long gene name: |
superoxide dismutase 1 |
| Synonyms gene: |
ALS ALS1 |
| Synonyms gene name: |
amyotrophic lateral sclerosis 1 (adult) superoxide dismutase 1, soluble |
| Synonyms: |
IPOA |
| Locus: |
21q22, 11 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AY049787 X02317 |
| Entrez gene record: |
6647 |
| Pubmed identfication: |
8446170 |
| RefSeq identity: |
NM_000454 |
| Havana BLAST/BLAT: |
OTTHUMG00000084878 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_652 |